Protease Chain Reaction (Pro-CR)
Overview
The primary goal of Pro-CR is to combine single-molecule level detection with signal amplification, resulting in a diagnostic technology that delivers unparalleled sensitivity and precise measurement.


 


Pro-CR combines a series of enzymatic components to create amplifying chain reactions.
The goals of Pro-CR are:
1) to detect vanishingly small quantities of an initiator molecule by exponentially amplifying its signal and
2) to determine the original concentration of the initiator molecule by using the time signature of the reaction.